Variation and mutation Cambridge IGCSE Co-ordinated Sciences (Double Award) revision

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In plain words

No two people are exactly alike, not even brothers and sisters. Some differences fall into clear groups: your blood group is A, B, AB or O, nothing in between. Others shade gradually from one extreme to the other, like height. Differences come from genes, from surroundings, or both.

Three things to know

  1. Discontinuous variation has a few distinct categories with nothing in between (blood group). It is caused by genes alone. Continuous variation has a complete range of values (height, mass). It is caused by genes and the environment together.
  2. A mutation is a change in a gene (a random change in the base sequence of DNA). It is how new alleles appear.
  3. Mutations happen naturally at random. Ionising radiation and some chemicals make them more likely.

Tips and tricks

  • Discontinuous: bar chart, separate bars. Continuous: histogram, a smooth hump with most people in the middle.
  • Most mutations have no effect; some are harmful; a few are useful.
5 questions, about 2 minutes.

It lands in your notebook with its questions as flashcards.

Variation and mutation: 5 questions and answers

These are the quiz’s questions. Do the quiz first, then come back here for the ones that got you.

  1. Which is an example of discontinuous variation?
    • height
    • mass
    • blood group (the answer)
    • hand span

    There are only four categories.

  2. What causes continuous variation?
    • genes only
    • environment only
    • genes and environment (the answer)
    • mutations only

    Height depends on your genes and on things like diet.

  3. What is a mutation?
    • a kind of cell division
    • a change in a gene (the answer)
    • a type of protein
    • an inherited disease

    It is a random change in the DNA.

  4. Which increases the rate of mutation?
    • exercise
    • ionising radiation (the answer)
    • sleep
    • a balanced diet

    Radiation can damage DNA.

  5. How do new alleles arise?
    • by mitosis
    • by mutation (the answer)
    • by diffusion
    • by respiration

    Mutation is the only source of new alleles.

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